Clinisciences > SLC25A4 Antibody - N-terminal region
SLC25A4 Antibody - N-terminal region
Referencia ARP43818_P050-25UL
embalaje : 25ul
Marca : Aviva Systems Biology
SLC25A4 Antibody - N-terminal region (ARP43818_P050)
| Datasheets/Manuals | Printable datasheet for anti-SLC25A4 (ARP43818_P050) antibody |
|---|
| Tested Species Reactivity | Human, Rat |
|---|---|
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human SLC25A4 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86% |
| Peptide Sequence | Synthetic peptide located within the following region: LLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-SLC25A4 (ARP43818_P050) antibody is Catalog # AAP43818 (Previous Catalog # AAPS14103) |
| Sample Type Confirmation | SLC25A4 is supported by BioGPS gene expression data to be expressed in RPMI 8226 |
| Enhanced Validation |
| Gene Symbol | SLC25A4 |
|---|---|
| Gene Full Name | Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 |
| Alias Symbols | T1, ANT, AAC1, ANT1, PEO2, PEO3, ANT 1, PEOA2, MTDPS12, MTDPS12A |
| NCBI Gene Id | 291 |
| Protein Name | ADP/ATP translocase 1 |
| Description of Target | This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. |
| Uniprot ID | Q05962 |
| Protein Accession # | NP_001142 |
| Nucleotide Accession # | NM_001151 |
| Protein Size (# AA) | 298 |
| Molecular Weight | 33 kDa |
| Protein Interactions | UBC; MDM2; PARK2; CLN5; CLN3; UBL4A; RPLP0P6; RPL10L; UQCRFS1P1; UQCRC1; RPS3A; RPS2; RPSA; GALNT2; UBD; COPS5; CDK2; TCF3; SUMO4; ICT1; NFKBIA; MGMT; PPID; PPIF; BAX; AR; PRKCE; NR3C1; |
Protein interactions
| Name | # of Products |
|---|---|
| AR | 434 |
| BAX | 99 |
| ICT1 | 287 |
| MGMT | 199 |
| NFKBIA | 240 |
| NR3C1 | 215 |
| PPID | 28 |
| PPIF | 5 |
| PRKCE | 118 |
| UBC | 7030 |
Biological pathways
| Name | # of Products |
|---|---|
| ADP transport | 1 |
| ATP transport | 3 |
| Glutamate uptake involved in synaptic transmission | 1 |
Biological process
| Name | # of Products |
|---|---|
| Adenine transport | 3 |
| ADP transport | 2 |
| Apoptotic mitochondrial changes | 18 |
| ATP transport | 6 |
| Energy reserve metabolic process | 72 |
| Generation of precursor metabolites and energy | 42 |
| Glutamate uptake involved in synaptic transmission | 3 |
| Interspecies interaction between organisms | 281 |
| Mitochondrial genome maintenance | 6 |
| Negative regulation of necrotic cell death | 9 |
| Regulation of insulin secretion | 77 |
| Small molecule metabolic process | 825 |
| Transmembrane transport | 500 |
| Transport | 555 |
| Viral reproduction | 279 |
Cellular components
| Name | # of Products |
|---|---|
| Integral to plasma membrane | 817 |
| Membrane | 2769 |
| Mitochondrial inner membrane | 251 |
| Mitochondrial outer membrane | 89 |
| Mitochondrion | 1154 |
Protein function
| Name | # of Products |
|---|---|
| Adenine transmembrane transporter activity | 1 |
| ATP:ADP antiporter activity | 3 |
| Enzyme binding | 898 |
| Protein binding | 12191 |
| Transporter activity | 360 |
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SLC25A4 ELISA Kit (Human) (OKEH02443)Catalog #: OKEH02443Application: ELISA-SandwichKit Range: 0.156-10ng/mLSensitivity: 0.087 ng/mL



