General Information
| Short Description | TLR12 Blocking Peptide for STJ503293 is synthetically produced from the 440-470 sequence and is suitable for use in western blot applications. |
| Applications | Immunodepletion/Immunocompetition |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Formulation | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Immunogen | Synthetic peptide taken within amino acid region 440-470 from mouse TLR12 protein. |
| Immunogen Region | 440-470 |
| Specificity | This blocking peptide is recommended for use in combination with TLR12 antibody, STJ503293 |
Additional Info
| Tissue Specificity | Macrophages, liver, kidney and bladder epithelial cells. |
| Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system. |
| Peptide Name | Toll-Like Receptor 12Toll-Like Receptor 11 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Toll-Like Receptor 12 proteinToll-Like Receptor 11 proteinTlr12 proteinGm1365 proteinTlr11 protein |
Information sourced from Uniprot.org