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Overview
Novel inhibitor of VDAC1 oligomerization and apoptosis
Reference:
1) Ben-Hail D, Begas-Shvartz R, Shalev M, Shteinfer-Kuzmine A, Gruzman A, Reina S, De Pinto V, Shoshan-Barmatz V. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003. Epub 2016 Oct 13. PubMed PMID: 27738100; PubMed Central PMCID: PMC5122769. Go To Paper Published Structure
Chemical Properties
| Molecular Formula | C21H23ClF3N3O3 |
| Molecular Weight | 457.88 |
| CAS Numbers | 2086257-77-2 (racemate) |
| Solubility | DMSO |
| Purity | 98% by HPLC |
Storage and Handling
0°C (short term), -20°C (long term), desiccated