(+/-)-Blebbistatin
Product Code
TRC-B592490
CAS Number
674289-55-5
Product Format
Neat
Molecular Formula
C18 H16 N2 O2
Molecular Weight
292.33
Documentation
Looking for another lot?
To view all certificates of analysis immediately, please login to your account
or
Find an SDS for your region
Product Information
Chemical Data
Analyte Name
(+/-)-Blebbistatin
CAS Number
674289-55-5
Molecular Formula
C18 H16 N2 O2
Molecular Weight
292.33
Accurate Mass
292.1212
SMILES
Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4
InChI
InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3
IUPAC
3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Format
Neat
Product Description
Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100uM.(±)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-oneSelective inhibitor of nonmuscle myosin II
References: Straight, A.F., et al.: Science, 299, 1743 (2003), Duxbury, M.S., et al.: Biochem. Biophys. Res. Commun., 313, 992 (2004), Kovacs, M., et al.: J. Biol. Chem., 279, 34 35557 (2004)
Related Products
- Product Code:
{{ isMultiplePacksize(product) ? getSourcePart(product) : product.code }} {{ isMultiplePacksize(product) ? getSourcePart(product) : product.code }}