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> (+/-)-Blebbistatin [674289-55-5]

(+/-)-Blebbistatin [674289-55-5]

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Referencia TRC-B592490-10MG

embalaje : 10mg

Marca : Toronto Research Chemicals

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(+/-)-Blebbistatin

Product Code

TRC-B592490

CAS Number

674289-55-5

Product Format

Neat

Molecular Formula

C18 H16 N2 O2

Molecular Weight

292.33

Documentation

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Product Information

Chemical Data

Analyte Name

(+/-)-Blebbistatin

CAS Number

674289-55-5

Molecular Formula

C18 H16 N2 O2

Molecular Weight

292.33

Accurate Mass

292.1212

SMILES

Cc1ccc2N=C3N(CCC3(O)C(=O)c2c1)c4ccccc4

InChI

InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3

IUPAC

3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one

Product Data

Storage Temperature

-20°C

Shipping Temperature

Room Temperature

Country of Origin

CANADA

Product Format

Neat

Product Description

Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. It blocks both blebbing and cytokinesis at 50-100uM.(±)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-oneSelective inhibitor of nonmuscle myosin II

References: Straight, A.F., et al.: Science, 299, 1743 (2003), Duxbury, M.S., et al.: Biochem. Biophys. Res. Commun., 313, 992 (2004), Kovacs, M., et al.: J. Biol. Chem., 279, 34 35557 (2004)