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> Acalabrutinib-d4 [2699608-18-7]

Acalabrutinib-d4 [2699608-18-7]

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Acalabrutinib-d4 is a deuterium labeled Acalabrutinib. Acalabrutinib (ACP-196) is an orally active, irreversible, and highly selective second-generation BTK inhibitor[1]. Acalabrutinib-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Acalabrutinib-d<sub>4</sub> Estructura química

Acalabrutinib-d4 Estructura química

No. CAS : 2699608-18-7

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5 mg USD 800 En stock
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Based on 1 publication(s) in Google Scholar

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Descripciòn

Acalabrutinib-d4 is a deuterium labeled Acalabrutinib. Acalabrutinib (ACP-196) is an orally active, irreversible, and highly selective second-generation BTK inhibitor[1]. Acalabrutinib-d4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Peso molecular

469.53

Fòrmula

C26H19D4N7O2
No. CAS
Appearance

Solid

Color

Light yellow to light brown

SMILES

O=C(NC1=NC([2H])=C([2H])C([2H])=C1[2H])C2=CC=C(C3=C4C(N)=NC=CN4C([C@H]5N(C(C#CC)=O)CCC5)=N3)C=C2
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Pureza y Documentación

Purity: 99.50%

COA (252 KB) LCMS (100 KB)

Instrucciones de manejo (2659 KB)
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Acalabrutinib-d4 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acalabrutinib-d42699608-18-7ACP-196-d4BtkBruton tyrosine kinaseorallyirreversibletyrosinephosphorylationERKIKBAKTCLLCys481on-targetchroniclymphocyticleukemiaPLCγ2Inhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
Acalabrutinib-d4
Cat. No.:
HY-17600S
Cantidad:
MCE Japan Authorized Agent: