ALPHA-PINENE [2437-95-8]

Referencia TL0003-200mg

embalaje : 200mg

Marca : TargetMol


ALPHA-PINENE

(Synonyms: (-)-Alpha-Pinene) Copy Product Info
ALPHA-PINENE ((-)-Alpha-Pinene) is a bicyclic monoterpene found in pine trees and other plants, including Cannabis with diverse biological activities [1]. It reduces the growth of a panel of seven Gram-positive bacteria, seven Gram-negative bacteria, and eight yeast strains with MIC values of 0.75-1.29, 1.05-1.59, and 0.7-1.17%, respectively [2]. It has insecticidal activity against C. molestus larvae with LC50 values ranging from 47 to 49 mg/L.3 ALPHA-PINENE (100 μg/ml) induces apoptosis, increases anion superoxide production and DNA fragmentation, and activates caspase-3 in B16/F10 melanoma cells [4]. In a B16/F10 mouse xenograft model, ALPHA-PINENE(100 ml of a 10 mg/ml solution) reduces the number of metastatic lung nodules by approximately 7-fold. ALPHA-PINENE(8.6 mg/L, aerosol) also increases the time spent in the open arms of the elevated plus maze by approximately 2-fold in mice, indicating anxiolytic-like activity [5].
ALPHA-PINENE
Cas No. 2437-95-8
Trade of this Product requires valid qualifications or certifications from both parties.
For research use only—not for human use. No sales to individuals. Use as intended only.
Select Batch
Purity:99.55%
Appearance:Liquid
Color:Transparent
COA HNMR GC

Product Introduction

Bioactivity
Description
ALPHA-PINENE ((-)-Alpha-Pinene) is a bicyclic monoterpene found in pine trees and other plants, including Cannabis with diverse biological activities [1]. It reduces the growth of a panel of seven Gram-positive bacteria, seven Gram-negative bacteria, and eight yeast strains with MIC values of 0.75-1.29, 1.05-1.59, and 0.7-1.17%, respectively [2]. It has insecticidal activity against C. molestus larvae with LC50 values ranging from 47 to 49 mg/L.3 ALPHA-PINENE (100 μg/ml) induces apoptosis, increases anion superoxide production and DNA fragmentation, and activates caspase-3 in B16/F10 melanoma cells [4]. In a B16/F10 mouse xenograft model, ALPHA-PINENE(100 ml of a 10 mg/ml solution) reduces the number of metastatic lung nodules by approximately 7-fold. ALPHA-PINENE(8.6 mg/L, aerosol) also increases the time spent in the open arms of the elevated plus maze by approximately 2-fold in mice, indicating anxiolytic-like activity [5].
Synonyms(-)-Alpha-Pinene
Chemical Properties
Molecular Weight136.23
FormulaC10H16
Cas No.2437-95-8
SmilesCC1=CCC2CC1C2(C)C
Relative Density.0.879g/cm3
Storage & Solubility Information
StorageStore at low temperature,Keep away from direct sunlight,Store under nitrogen,Keep away from moisture Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 20 mg/mL (146.81 mM), Sonication is recommended.
Ethanol: 20 mg/mL (146.81 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Saline: 10 mg/mL (73.41 mM), Suspension.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM7.3405 mL36.7026 mL73.4053 mL367.0264 mL
5 mM1.4681 mL7.3405 mL14.6811 mL73.4053 mL
10 mM0.7341 mL3.6703 mL7.3405 mL36.7026 mL
20 mM0.3670 mL1.8351 mL3.6703 mL18.3513 mL
50 mM0.1468 mL0.7341 mL1.4681 mL7.3405 mL
100 mM0.0734 mL0.3670 mL0.7341 mL3.6703 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.