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> Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi)

Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi)

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Referencia NB-64-128462-500ug

embalaje : 500ug

Marca : Neo Biotech


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Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi)

(Synonyms: Integrin α V β 3, Integrin alpha V β3) Copy Product Info

Synonyms: Integrin α V β 3, Integrin alpha V β3

Catalog No. TMPY-05716U Copy Product Info
Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3).
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Bis-Tris PAGE
Appearance:Lyophilized powder
Color:White
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Product Information

Bioactivity
Bioactivity
Immobilized Human ITGAV&ITGB3, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 9.2 ng/ml determined by ELISA.
Description
Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 Cells. The accession number is P06756-1(ITGAV)&P05106-1(ITGB3).
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberP06756-1(ITGAV)&P05106-1(ITGB3)
ConstructionPhe31-Val992(ITGAV)acidic tail & Gly27-Asp718(ITGB3)basic tail
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
ReconstitutionReconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsIntegrin α V β 3, Integrin alpha V β3
Research Background
ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Chemical Properties
Molecular Weight114 kDa (ITGAV) & 81.3 kDa (ITGB3) (Predicted); 85-140 kDa (Due to glycosylation)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

TMPY-05716
Related Tags: Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) chemical structure | Integrin alpha V beta 3 Protein, Human, Recombinant (His & Avi) molecular weight