Webinar: Preventing Sample Mix-Ups in NGS

Live Webinar Invitation
Date: Tuesday, 28 April 2026 | Time: 11:00 AM CET

Next-Generation Sequencing has become central to modern genomic diagnostics, from rare disease identification to precision oncology. However, the complexity of library preparation workflows introduces a persistent risk of sample swaps and mislabeling, estimated at around 1% of datasets. Such errors can lead to misdiagnosis and serious clinical consequences.

In this webinar, we will present SNPXplex®, a simple and affordable identitovigilance solution developed at the French AP-HP, the largest academic hospital network in Europe, to secure NGS analyses. Based on a unique multiplex PCR targeting selected SNPs, SNPXplex® generates a genetic barcode that can be rapidly compared with NGS data.

The method requires less than 15 minutes of hands-on time, uses standard molecular genetics equipment, and provides results in just a few hours.

Join us to discover how SNPXplex® can be easily integrated into routine workflows to ensure sample identity and strengthen the reliability of genomic diagnostics.

Overview

SNPXplex® is a patented identity vigilance kit developed by the Assistance Publique–Hôpitaux de Paris (AP-HP) and exclusively produced and commercialized by Bioxtal. The kit enables simultaneous genotyping of 15 carefully selected single nucleotide polymorphisms (SNPs) plus sex determination through a ready-to-use allele-specific fluorescent multiplex PCR. The resulting genetic barcode is compared directly with NGS genotyping data to confirm sample identity and detect potential mix-ups.

Fully compatible with targeted panels, exomes, genomes, capture, and amplicon-based NGS methods, SNPXplex® operates on standard laboratory equipment (thermal cycler and capillary sequencer with 6-FAM™ detection). It has been in routine clinical use since 2017, securing more than 100,000 NGS analyses while maintaining a very low probability of profile collision. Attendees will gain practical insights into this cost-effective, high-reliability solution that complements existing NGS workflows and supports best-practice recommendations for genoidentity verification in precision medicine.