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> Anti-ENTPD2 Polyclonal Antibody

Anti-ENTPD2 Polyclonal Antibody

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Referencia NB-64-155547-200uL

embalaje : 200uL

Marca : Neo Biotech


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Anti-ENTPD2 Polyclonal Antibody

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Synonyms:

Catalog No. TMAB-05596 Copy Product Info
Anti-ENTPD2 Polyclonal Antibody is a Rabbit antibody targeting ENTPD2. Anti-ENTPD2 Polyclonal Antibody can be used in WB.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Description
Anti-ENTPD2 Polyclonal Antibody is a Rabbit antibody targeting ENTPD2. Anti-ENTPD2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Cow,Sheep)
Verified Activity
Sample: Cerebrum (Rat) Lysate at 40 μg
Primary: Anti-ENTPD2 (TMAB-05596) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein
Tissue SpecificityBrain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENP1), is an integral membrane glycoprotein that acts as an extracellular nucleotide-hydrolyzing enzyme. CD39 inhibits ADP-induced platelet aggregation by hydrolyzing ADP to AMP and ultimately generating adenosine. Intracellular CD39 undergoes glycosylation at 6 N-glycosylation sites and translocates to the membrane in order to be an active enzyme. CD39L1 is a 495 amino acid multi-pass membrane protein that requires calcium and magnesium cofactors to hydrolyze ATP and other nucleotides in the regulation of purigenic neurotransmission. CD39L1 is expressed in kidney, colon, heart, testis, pancreas, brain, prostate, skeletal muscle, small intestine and ovaries. There are two isoforms of CD39L1 that are produced as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ENTPD2/CD39L1
Antigen Species
Human
Gene Name
ENTPD2
Gene ID
954
Protein Name
Ectonucleoside triphosphate diphosphohydrolase 2
Uniprot ID
Q9Y5L3
Function
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent.
Chemical Properties
Molecular WeightTheoretical: 54 kDa. Actual: 54 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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