Basiliximab [179045-86-4]
Referencia NB-64-41394-1mg
embalaje : 1mg
Marca : Neo Biotech
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Basiliximab
(Synonyms: CHI 621) Copy Product InfoSynonyms: CHI 621
Catalog No. T73698 Copy Product Info
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody targeting the interleukin-2 receptor, demonstrating potent immunosuppressive activity for use in kidney transplantation studies.
Cas No. 179045-86-4
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:94.1% (SDS-PAGE); 95.3% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody targeting the interleukin-2 receptor, demonstrating potent immunosuppressive activity for use in kidney transplantation studies. |
| In vitro | Specifically inhibiting T lymphocyte proliferation, Basiliximab binds to IL-2Rα[1]. It binds only to activated lymphocytes and macrophages/monocytes[3]. Basiliximab does not affect resting T lymphocytes that do not express IL-2Rα[2]. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | CHI 621 |
| Reactivity | Human |
| Verified Activity | Immobilized Human CD25/IL2R Protein (His) (TMPY-01103) at 1 μg/mL (100 μL/well) can bind Basiliximab. The EC50 is 3.33 ng/mL.  |
| Application | ELISA FCM Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | 3559 |
| Uniprot ID | P01589 |
| Target | IL-2Ra/CD25 |
| Molecular Weight | 144.01 kDa |
| Cas No. | 179045-86-4 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control | Human IgG1 kappa, Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Keywords
Interleukin RelatedCHI-621CHI621Basiliximab
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Related Tags: Basiliximab chemical structure | Basiliximab in vitro | Basiliximab molecular weight
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