GZMB (Human) ELISpot Kit

Quantification

Entrez GeneID

Gene Name

GZMB

Gene Alias

CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT

Gene Description

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

Omim ID

Gene Ontology

Gene Summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq

Other Designations

T-cell serine protease 1-3E|cathepsin G-like 1|cytotoxic serine protease B|fragmentin 2|granzyme B