General Information
| Short Description | This Matrix Metalloproteinase-9 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and cell culture supernates. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 15.2 pg/mL |
| Detection Limit | 312-2000 pg/ml |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Biotin |
| Storage Instruction | Unopened kits can be stored at 2-8°C for 1 year, and opened products must be used within 1 month. |
| Assay Time | 4 hours |
| Detection | Colorimetric |
Target Information
| Gene Symbol | |
| Gene ID | |
| Uniprot ID | |
| Sample Type | serum, plasma and cell culture supernates |
Additional Info
| Tissue Specificity | Detected in neutrophils (at protein level). Produced by normal alveolar macrophages and granulocytes. |
| Post Translational Modifications | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. |
| Function | Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. |
| Protein Name | Matrix Metalloproteinase-9Mmp-992 Kda Gelatinase92 Kda Type Iv CollagenaseGelatinase BGelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative ELISA Names | Matrix Metalloproteinase-9 ELISA kitMmp-9 ELISA kit92 Kda Gelatinase ELISA kit92 Kda Type Iv Collagenase ELISA kitGelatinase B ELISA kitGelb Cleaved Into - 67 Kda Matrix Metalloproteinase-9 - 82 Kda Matrix Metalloproteinase-9 ELISA kitMMP9 ELISA kitCLG4B ELISA kit |
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Information sourced from Uniprot.org