MIP1 beta antibody
Referencia GTX10383-25ug
embalaje : 25ug
Marca : Genetex
Contact local distributor :
Teléfono : +1 850 650 7790
Host | Goat |
|---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | WB, IHC-Fr, ELISA, Neutralizing/Inhibition |
Reactivity | Human |
| Package | 25 μg |
Datasheet File View product citations for antibody GTX10383 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| WB | Assay dependent |
| IHC-Fr | Assay dependent |
| ELISA | Assay dependent |
| Neutralizing/Inhibition | Assay dependent |
Not tested in other applications.
Calculated MW
10 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Purified insect cell line Sf21-derived recombinant human MIP-1beta.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
C-C motif chemokine ligand 4 , ACT2 , AT744.1 , G-26 , HC21 , LAG-1 , LAG1 , MIP-1-beta , MIP1B , MIP1B1 , SCYA2 , SCYA4
Cellular Localization
Secreted
Background
MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD-5a. The predicted protein products of these cDNAs represent variants that are between 94% - 98% identical and these proteins are all approximately 75% homologous to murine MIP1 beta. MIP1 beta also shares approximately 70% amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.
Database
REVIEW
| SDS | |
|---|---|
| PBS.pdf | |