Mouse Nodal activation kit by CRISPRa

Referencia GA202929

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Mouse Nodal activation kit by CRISPRa

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SKU
GA202929
Nodal CRISPRa kit - CRISPR gene activation of mouse nodal
 
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Nodal
Locus ID 18119
Components

GA202929G1, Nodal gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA202929G2, Nodal gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA202929G3, Nodal gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013611
UniProt ID P43021
Synonyms Tg.413d
Summary This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. Homozygous knockout mice for this gene exhibit early embryonic lethality, while expression of a hypomorphic allele results in defects in anteroposterior and left-right patterning. provided by RefSeq, Aug 2016
SKU Description Size
KN511097 Nodal - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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