RNASEH2B Antibody is a Rabbit Polyclonal antibody against RNASEH2B. RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2).
Research Articles on Ribonuclease H2 Subunit B (RNASEH2B)
| Target | Ribonuclease H2 Subunit B (RNASEH2B) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human RNASEH2B |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q5TBB1 (UniProt, ExPASy) |
| UniProt Secondary AC | G3XAJ1, Q05DR2, Q6PK48, Q9HAF7 |
| UniProt Entry Name | RNH2B_HUMAN |
| Gene Symbol | RNASEH2B |
| GeneID | 79621 |
| NCBI Accession | NP_078846.2 |
| KEGG | hsa:79621 |
| String | 9606.ENSP00000337623 |
| Molecular Weight | Calculated MW: 29 kDa/35 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |