TLR9 - human gene knockout kit via CRISPR, HDR mediated
Other products for "TLR9 or NM_017442"
Specifications
Product Data
Format
2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Vector
Luciferase-Puro
Target Symbol
TLR9
Locus ID
54106
Components
KN207510G1, TLR9 gRNA vector 1 in pCas-Guide CRISPR vector
KN207510G2, TLR9 gRNA vector 2 in pCas-Guide CRISPR vector
KN207510LPD, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.
GE100003, scramble sequence in pCas-Guide vector
OTI Disclaimer
These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. provided by RefSeq, Aug 2017
TLR9 CRISPRa kit - CRISPR gene activation of human toll like receptor 9
1 kit
KN207510
TLR9 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN207510BN
TLR9 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN207510RB
TLR9 - human gene knockout kit via CRISPR, HDR mediated
1 kit
KN407510
TLR9 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
1 kit
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
