Sulfathiazole (sodium) [144-74-1]
Referência HY-B0507A-1g
Tamanho : 1g
Marca : MedChemExpress
Sulfathiazole sodium is an organosulfur compound that has been used as a short-acting sulfa drug.
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Sulfathiazole sodium Chemical Structure
CAS No. : 144-74-1
This product is a controlled substance and not for sale in your territory.
Based on 3 publication(s) in Google Scholar
Other Forms of Sulfathiazole sodium:
- Sulfathiazole In-stock
- Sulfathiazole-d4 In-stock
Description |
Sulfathiazole sodium is an organosulfur compound that has been used as a short-acting sulfa drug. Target: Antibacterial Sulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3) [1]. Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level [2]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species [3]. |
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Masse moléculaire |
277.30 |
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Formule |
C9H8N3NaO2S2 |
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CAS No. |
144-74-1 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=S(C1=CC=C(N)C=C1)([N-]C2=NC=CS2)=O.[Na+] |
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Livraison | Room temperature in continental US; may vary elsewhere. |
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Stockage |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Solvant et solubilité |
In Vitro:
DMSO : 140 mg/mL (504.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) H2O : 140 mg/mL (504.87 mM; Need ultrasonic) Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Pureté et documentation |
Purity: 99.92% |
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Références |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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DMSO / H2O | 1 mM | 3.6062 mL | 18.0310 mL | 36.0620 mL | 90.1551 mL |
5 mM | 0.7212 mL | 3.6062 mL | 7.2124 mL | 18.0310 mL | |
10 mM | 0.3606 mL | 1.8031 mL | 3.6062 mL | 9.0155 mL | |
15 mM | 0.2404 mL | 1.2021 mL | 2.4041 mL | 6.0103 mL | |
20 mM | 0.1803 mL | 0.9016 mL | 1.8031 mL | 4.5078 mL | |
25 mM | 0.1442 mL | 0.7212 mL | 1.4425 mL | 3.6062 mL | |
30 mM | 0.1202 mL | 0.6010 mL | 1.2021 mL | 3.0052 mL | |
40 mM | 0.0902 mL | 0.4508 mL | 0.9016 mL | 2.2539 mL | |
50 mM | 0.0721 mL | 0.3606 mL | 0.7212 mL | 1.8031 mL | |
60 mM | 0.0601 mL | 0.3005 mL | 0.6010 mL | 1.5026 mL | |
80 mM | 0.0451 mL | 0.2254 mL | 0.4508 mL | 1.1269 mL | |
100 mM | 0.0361 mL | 0.1803 mL | 0.3606 mL | 0.9016 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.