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> β-D-Glucan [9041-22-9]

β-D-Glucan [9041-22-9]

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Cat# orb1983179-50mg

Size : 50mg

Brand : Biorbyt


β-D-Glucan

SKU: orb1983179

Description

This research-grade β-D-Glucan is a bioactive small molecule known for its antitumor activity via targeting tumor-associated macrophages. It also modulates immune responses, showing relevance in models of necrotizing pancreatitis. Its applications span immunology and oncology research in both in vitro and in vivo experimental settings.

Research Area

Immunology & Inflammation

Images & Validation

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β-D-Glucan

Key Properties

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CAS Number9041-22-9
MW504.438
Purity95.00% (May vary between batches)
FormulaC18H32O16
SMILES04[C@]1(CO)O[C@](04)(O)[C@](04)(O)[C@@](04)(O)C1O[C@]1(04)O[C@](04)(CO)C(O[C@]2(04)O[C@](04)(CO)[C@@](04)(O)[C@](04)(O)[C@@]2(04)O)[C@](04)(O)[C@@]1(04)O
TargetOthers,TLR
SolubilityNaOH:10 mg/mL

Bioactivity

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In Vitro
Dissolving β-D-glucan in DMSO, but not in water, results in a concentration-dependent inhibition of MCF-7 cell proliferation, as determined by BrdU incorporation, with an IC50 of approximately 164 μg/mL. β-D-glucan, when dissolved in DMSO, inhibits the proliferation of tamoxifen/endocrine-resistant LCC9 and LY2 cells with IC50 values of 4.6 and 24.2 μg/mL, respectively.

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quick Database Links

Gene Symbol
Others,TLR

Protocol Information