Reagents and instruments for immunology, cell biology and molecular biology.
 
Fetal bovine serum

Fetal bovine serum

Fetal Bovine Serum (FBS) is a widely used supplement in cell culture, essential for supporting the growth and maintenance of various mammalian cells in vitro. It is prized for its rich content of nutrients and growth factors, making it a cornerstone in life science research and biotechnology.

Origin and Production of FBS

FBS is derived from the blood of bovine fetuses, collected aseptically from pregnant cows at slaughterhouses. The process involves a closed system to ensure sterility and high quality. After collection, the blood is allowed to clot, and the serum—the liquid fraction—is separated by removing cells and coagulation factors.

Composition and Key Components

FBS contains a complex mixture of over 1,000 components, including proteins, hormones, growth factors, vitamins (such as A, D, E, and K), lipids, amino acids, carbohydrates, minerals, and enzymes. These constituents collectively create an environment conducive to cell survival, proliferation, and differentiation.

Role of FBS in Cell Culture

In cell culture, FBS provides essential nutrients and growth-promoting factors that support cell viability and function. It also contains protective agents like protease inhibitors and buffering substances, which help maintain optimal culture conditions. Additionally, FBS facilitates cell adhesion by coating culture vessel surfaces, enhancing cell attachment and growth.

Applications of FBS in Research and Industry

  • Animal Diagnostics: Used for diagnostic testing on animal samples.
  • Cloning: Supports cellular cloning processes.
  • Cryopreservation: Aids in preserving cells for long-term storage.
  • Stem Cell Research: Provides a supportive environment for stem cell culture.
  • Biopharmaceutical and Vaccine Production: Essential for manufacturing biopharmaceuticals and vaccines.
  • Cell and Gene Therapy: Supports the development of advanced therapies.
  • Immunotherapy: Facilitates cell culture for immunotherapeutic applications.
  • Viral Vector Manufacturing: Used in the production of viral vectors for gene therapy.

Quality Control and Consistency

Due to its biological origin, FBS composition can vary between lots. Manufacturers implement rigorous testing for contaminants such as endotoxins, mycoplasma, and viruses to ensure safety and reliability. Lot-matching tools are also provided to help researchers maintain consistency across experiments.


Frequently Asked Questions (FAQ)

Where can I find fbs products on the CliniSciences website?

fbs products are available in this section and can be sorted by product families or sub-categories, such as FBS of different origins, FBS Xtra, Other sera. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.

What types of products are available in the fbs category?

The fbs category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The FBS with different qualifications , FBS advanced, FBS Xtra sub-categories allow you to find the products that meet your needs more quickly.

How can I quickly find a fbs product?

To find a fbs product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does CliniSciences stock several product codes in the fbs category?

Yes, CliniSciences distributes several product references in the fbs category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for fbs products?

Yes, you can request a quote for fbs products from the product page or by contacting CliniSciences (info@clinisciences.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a fbs product is available to order?

The availability of a fbs product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact CliniSciences with the product code or name of the product you are looking for.

What should I do if I cannot find the fbs product I am looking for?

If the fbs product you are looking for does not appear in the catalogue, please contact CliniSciences with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all fbs products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.