Mouse biological fluids are widely used in biomedical research because they provide direct insight into physiological and pathological processes while reflecting the complex molecular composition of the in vivo environment. Commonly studied specimens include serum, plasma, whole blood, cerebrospinal fluid (CSF), urine, bronchoalveolar lavage fluid (BALF), synovial fluid, milk, saliva, and reproductive fluids. These samples contain proteins, metabolites, lipids, extracellular vesicles, nucleic acids, cytokines, chemokines, hormones, immunoglobulins, and circulating cells that reflect systemic and tissue-specific biological responses. Mouse biological fluids are therefore essential for investigating disease mechanisms, biomarker discovery, pharmacokinetics, toxicology, immunology, metabolism, neuroscience, oncology, cardiovascular biology, and infectious diseases. Standardized collection, processing, and storage procedures are critical for minimizing pre-analytical variability and ensuring reproducible molecular analyses.
Key Features
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Physiologically Relevant Biological Matrices : Native biological matrices reflecting physiologically relevant molecular composition.
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Broad Multi-Omics Compatibility: Compatible with proteomics, metabolomics, lipidomics, extracellular vesicle characterization, extracellular and cell-free nucleic acid analyses, and biomarker discovery.
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Suitable for Longitudinal Studies : Suitable for longitudinal studies where repeated sampling is feasible while adhering to animal welfare and experimental design considerations.
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Wide Research Utility : Applicable to immunological, endocrine, metabolic, neurological, cardiovascular, inflammatory, and infectious disease research.
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Compatible with Standard Analytical Platforms : Compatible with ELISA, multiplex immunoassays, flow cytometry, mass spectrometry, PCR, next-generation sequencing, and biochemical or clinical chemistry assays.
Typical Research Applications
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Biomarker discovery and validation.
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Pharmacokinetic and toxicological studies.
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Immune response, cytokine, and chemokine profiling.
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Cancer biology and circulating biomarker research.
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Metabolic disease and endocrine investigations.
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Neurodegeneration and central nervous system biomarker studies using CSF.
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Infectious disease, inflammation, and host–pathogen interaction research.