Reagents and instruments for immunology, cell biology and molecular biology.

MYC probe for ISH CE/IVD - Gastrointestinal pathology

The MYC proto-oncogene (MYC proto-oncogene, bHLH transcription factor, a.k.a. CMYC) is located in the chromosomal region 8q24.21 and encodes a transcription factor that can activate and repress transcription thereby regulating expression of numerous target genes that are essential for cell growth and proliferation.

Deregulation of MYC is a common denominator in cancer. MYC amplification was found e.g. in breast, colon, kidney, lung, ovary, bladder, head and neck, and endometrial cancer. Several studies showed a correlation between gene amplification and disease progression or recurrence in breast cancer and other malignancies.

Malignant cutaneous angiosarcomas, for example, but not benign and atypical vascular lesions occurring after radiotherapy of breast cancer are characterized by amplification of the MYC gene. The presence of MYC amplification is thus of considerable diagnostic importance for the distinction of malignant from atypical postradiation vascular neoplasms of the skin.

Since inactivation of MYC appears to be effective in the treatment of neoplasia MYC targeting therapies have been developed some of which have entered clinical trials.

FISH

Frequently Asked Questions (FAQ)

Where can I find myc products on the CliniSciences website?

myc products are available in this section and can be sorted by product families or sub-categories, such as FISH. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.

What types of products are available in the myc category?

The myc category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The FISH sub-categories allow you to find the products that meet your needs more quickly.

How can I quickly find a myc product?

To find a myc product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does CliniSciences stock several product codes in the myc category?

Yes, CliniSciences distributes several product references in the myc category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for myc products?

Yes, you can request a quote for myc products from the product page or by contacting CliniSciences (info@clinisciences.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a myc product is available to order?

The availability of a myc product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact CliniSciences with the product code or name of the product you are looking for.

What should I do if I cannot find the myc product I am looking for?

If the myc product you are looking for does not appear in the catalogue, please contact CliniSciences with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all myc products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.