Reagents and instruments for immunology, cell biology and molecular biology.

NTRK2 probe for ISH CE/IVD - Brain and neural pathology

NTRK2 (Neurotrophic Receptor Tyrosine Kinase 2) gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. NTRK2 is altered by mutation or chromosomal rearrangement in a diverse range of cancers. Alternative splicing results in multiple transcript variants.

Fusions, missense, nonsense, and silent mutations of NTRK2 gene are observed in cancers such as intestinal cancer, skin cancer, and stomach cancer. NTRK2 is altered in 1.27% of all cancers with lung adenocarcinoma, colon adenocarcinoma, cutaneous melanoma, endometrial endometrioid adenocarcinoma, and bladder urothelial carcinoma having the greatest prevalence of alterations.

FISH

Frequently Asked Questions (FAQ)

Where can I find ntrk2 products on the CliniSciences website?

ntrk2 products are available in this section and can be sorted by product families or sub-categories, such as FISH. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.

What types of products are available in the ntrk2 category?

The ntrk2 category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The FISH sub-categories allow you to find the products that meet your needs more quickly.

How can I quickly find a ntrk2 product?

To find a ntrk2 product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does CliniSciences stock several product codes in the ntrk2 category?

Yes, CliniSciences distributes several product references in the ntrk2 category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for ntrk2 products?

Yes, you can request a quote for ntrk2 products from the product page or by contacting CliniSciences (info@clinisciences.com). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a ntrk2 product is available to order?

The availability of a ntrk2 product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact CliniSciences with the product code or name of the product you are looking for.

What should I do if I cannot find the ntrk2 product I am looking for?

If the ntrk2 product you are looking for does not appear in the catalogue, please contact CliniSciences with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all ntrk2 products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.