SARS-CoV-2 - ELISA kits - Spike protein
The SARS-CoV-2 virus, the cause of the current Covid-19 pendemia, can infect human respiratory epithelial cells through an interaction with the human ACE2 receptor or angiotensin converting enzyme receptor 2. SARS-CoV-2 has on its surface a protein called Spike or S protein. This type I transmembrane protein is present on the viral envelope in the form of a homotrimer. Each monomer consists of 2 subunits, S1 and S2. The S1 subunit contains a receptor binding domain (RBD) which binds to the ACE2 receptor on the host membrane. The S2 sub-unit is activated by the bond between S1 and the ACE2 receptor and contains the elements necessary for membrane fusion. The S protein thus plays an important role in the infection of SARS-CoV-2 as well as in the induction of neutralizing antibody and T cell responses and in protective immunity.
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RUOCE / IVD
- Biotin 8
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- SARS-CoV-2 4
- COVID-19 1
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- human 115
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- 32.22 pg/mL 3
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- < 1.0 EU/μg of the protein by LAL method. 1
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- 1A9 / HL263 1
- HL1014 / HL1003 1
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NB-22-71807
96T
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